Journal:Informatica
Volume 24, Issue 4 (2013), pp. 505–521
Abstract
Two mathematical models of an amperometric bienzyme biosensor are analysed digitally. The models hold different boundary conditions describing the singularity of the electrode (transducer). The influence of the initial and boundary conditions on the biosensors action at different sets of parameters is analysed.
The digital simulation at the transient and steady-state conditions was carried out by using finite difference technique. The comparison of the simulation results revealed that some of the calculated parameters, i.e. response and sensitivity is the same, while the others, i.e. half-time of the steady-state is significantly different for distinct models.
Journal:Informatica
Volume 22, Issue 4 (2011), pp. 589–600
Abstract
The concentration of a substrate in a solution can be measured using amperometric signals of biosensors: in fact the maximum (steady state) current is measured which is calibrated in the units of concentration. Such a simple method is not applicable in the case of several substrates. In the present paper, the problem of evaluation of concentrations of several substrates is tackled by minimizing the discrepancy between the observed and modeled transition processes of the amperometric signal.