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Behavioural Representation of the Aorta by Utilizing Windkessel and Agent-Based Modelling
Volume 32, Issue 3 (2021), pp. 499–516
Pub. online: 30 July 2021      Type: Research Article      Open accessOpen Access
Received
1 November 2020
Accepted
1 July 2021
Published
30 July 2021

Abstract

The main objective of the present paper is to report two studies on mathematical and computational techniques used to model the behaviour of the aorta in the human cardiovascular system. In this paper, an account of the design and implementation of two distinct models is presented: a Windkessel model and an agent-based model. Windkessel model represents the left heart and arterial system of the cardiovascular system in the physiological domain. The agent-based model offers a simplified account of arterial behaviour by randomly generating arterial parameter values. This study has described the mechanism how and when the left heart contracts and pumps the blood out of the aorta, and it has taken the Windkessel model one step further. The results of this study show that the dynamics of the aorta can be explored in each modelling approaches as proposed and implemented by our research group. It is thought that this study will contribute to the literature in terms of development of the Windkessel model by considering its timing and redesigning it with digital electronics perspective.

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Biographies

Emek Sevcan
sevcan.emek@cbu.edu.tr

S. Emek received her PhD degree from Ege University, Turkey, in 2018. She is currently a research assistant in the Computer Engineering Department at Manisa Celal Bayar University. Her research interests include artificial intelligence, control systems and agent-based modelling and simulation.

Bora Şebnem
sebnem.bora@ege.edu.tr

Ş. Bora received her PhD degree from Ege University, Turkey, in 2006. She is currently an associate professor in the Computer Engineering Department at Ege University. Her research interests include dependable computing, self-adaptive systems, agent based modelling and simulation.

Evren Vedat
vedat.evren@ege.edu.tr

V. Evren is an MD-PhD at the Ege University School of Medicine, Department of Physiology, Izmir, Turkey. He is currently an associate professor in the Department of Physiology at Ege University.

Çakirlar İbrahim
icakirlar@gmail.com

İ. Çakırlar received the BS, MS and PhD degrees in computer engineering from Computer Engineering Department of Ege University in 2007, 2009 and 2015, respectively. He is currently a software engineer in Concur France SAS.


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Open access article under the CC BY license.

Keywords
agent agent-based modelling and simulation blood vessel agent Windkessel model

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