Journal:Informatica
Volume 22, Issue 4 (2011), pp. 589–600
Abstract
The concentration of a substrate in a solution can be measured using amperometric signals of biosensors: in fact the maximum (steady state) current is measured which is calibrated in the units of concentration. Such a simple method is not applicable in the case of several substrates. In the present paper, the problem of evaluation of concentrations of several substrates is tackled by minimizing the discrepancy between the observed and modeled transition processes of the amperometric signal.
Journal:Informatica
Volume 21, Issue 3 (2010), pp. 409–424
Abstract
The paper addresses the over-saturated protein spot detection and extraction problem in two-dimensional electrophoresis gel images. The effective technique for detection and reconstruction of over-saturated protein spots is proposed. The paper presents: an algorithm of the median filter mask adaptation for initial filtering of gel image; the models of over-saturation used for gel image analysis; several models of protein spots used for reconstruction; technique of the automatic over-saturated protein spot search and reconstruction. Experimental investigation confirms that proposed search technique lets to find up to 96% of over-saturated protein spots. Moreover the proposed flexible protein spot shape models for reconstruction are faster and more accurate in comparison to the flexible diffusion model.
Journal:Informatica
Volume 18, Issue 2 (2007), pp. 253–266
Abstract
The method for calculating the specific conductivity tensor of an anisotropically conductive medium, proposed in this paper, distinguishes itself by the simplicity of physical measurements: it suffices to make an equally thick rectangle-shaped sample with four electrodes fixed on its sides and to take various measurements of current intensity and differences of potentials. The necessary mathematical calculations can be promptly performed, even without using a complex computing technique. The accuracy of the results obtained depends on the dimensions of the sample and on the ratios of the conductivity tensor components.
Journal:Informatica
Volume 13, Issue 4 (2002), pp. 485–500
Abstract
This paper presents model-based forecasting of the Lithuanian education system in the period of 2001–2010. In order to obtain satisfactory forecasting results, development of models used for these aims should be grounded on some interactive data mining. The process of the development is usually accompanied by the formulation of some assumptions to background methods or models. The accessibility and reliability of data sources should be verified. Special data mining of data sources may verify the assumptions. Interactive data mining of the data, stored in the system of the Lithuanian teachers' database, and that of other sources representing the state of the education system and demographic changes in Lithuania was used. The models cover the estimation of data quality in the databases, analysis of the flow of teachers and pupils, clustering of schools, the model of dynamics of the pedagogical staff and pupils, and the quality analysis of teachers. The main results of forecasting and integrated analysis of the Lithuanian teachers' database with other data reflecting the state of the education system and demographic changes in Lithuania are presented.
Journal:Informatica
Volume 13, Issue 4 (2002), pp. 405–416
Abstract
A model of the moisture diffusion in wood under isothermal conditions taking into consideration coating of the surface of a specimen is presented in a 2-D-in-space formulation. A reliability of a corresponding 1-D model is investigated for a simulation of moisture movement in 2-D medium. This paper presents a technique to determine the width as well as the degree of edges coating of the specimen making the 1-D model relevant for 2-D medium. This technique bases on the computer simulation of 2-D moisture diffusion to estimate the reliability of the corresponding 1-D model. In the technique, approximate coefficients of the diffusion and surface emission may be employed if accurate values of these coefficients are unknown.