Informatica

This work compares different algorithms to replace the genetic optimizer used in a recent methodology for creating realistic and computationally efficient neuron models. That method focuses on single-neuron processing and has been applied to cerebellar granule cells. It relies on the adaptive-exponential integrate-and-fire (AdEx) model, which must be adjusted with experimental data. The alternatives considered are: i) a memetic extension of the original genetic method, ii) Differential Evolution, iii) Teaching-Learning-Based Optimization, and iv) a local optimizer within a multi-start procedure. All of them ultimately outperform the original method, and the last two do it in all the scenarios considered.

This paper models and solves the scheduling problem of cable manufacturing industries that minimizes the total production cost, including processing, setup, and storing costs. Two hybrid meta-heuristics, which combine simulated annealing and variable neighbourhood search algorithms with tabu search algorithm, are proposed. Applying some case-based theorems and rules, a special initial solution with optimal setup cost is obtained for the algorithms. The computational experiments, including parameter tuning and final experiments over the benchmarks obtained from a real cable manufacturing factory, show superiority of the combination of tabu search and simulated annealing comparing to the other proposed hybrid and classical meta-heuristics.