The Hamiltonian cycle and path problems are fundamental in graph theory and useful in modelling real-life problems. Research in this area is directed toward designing better and better algorithms for general problems, but also toward defining new special cases for which exact polynomial-time algorithms exist. In the paper, such new classes of digraphs are proposed. The classes include, among others, quasi-adjoint graphs, which are a superclass of adjoints, directed line graphs, and graphs modelling a DNA sequencing problem.