The theory of T-spherical fuzzy (T-SF) sets possesses remarkable capability to manage intricate uncertain information. The REGIME method is a well-established technique concerning discrete choice analysis. This paper comes up with a multiple-criteria choice analysis approach supported by the REGIME structure for manipulating T-SF uncertainties. This paper constructs new-created measurements such as superiority identifiers and guide indices for relative attractiveness and fittingness, respectively, between T-SF characteristics. This study evolves the T-SF REGIME I and II prioritization procedures for decision support. The application and comparative studies exhibit the effectiveness and favorable features of the propounded T-SF REGIME methodology in real decisions.